NEJM Journal Watch: Oncology And Hematology RSS Feed
Underrecognition of Symptoms Caused by Breast Radiation Therapy
Radiation oncologists underrecognized common symptoms of acute toxicity in more than half of patients, and more often in Black patients than white patients.
New Prevalence Data on Monoclonal Gammopathies
With sensitive detection techniques, >10% of people older than 50 had monoclonal gammopathy of undetermined significance.
BRCA1 and BRCA2: Risk Beyond Breast and Ovarian Cancer
Data from Japan suggest that pathogenic variants are associated with increased risk for a broad group of malignancies.
Do Advance Directives Undermine Advance Care Planning£
In this qualitative study, patients sometimes viewed advance directives as a substitute for, rather than an adjunct to, goals-of-care discussions.
Segmentectomy Is Supported as Standard of Care for Small, Peripheral Non–Small-Cell Lung Cancer
In a randomized trial, segmentectomy was noninferior to lobectomy in terms of overall survival.
Mitapivat for the Treatment of Pyruvate Kinase Deficiency
An activator of red cell pyruvate kinase improved hemoglobin and quality of life in patients with PK deficiency.
More Support for Nivolumab plus Chemotherapy in Gastric Cancer
The addition of nivolumab was associated with improvement in progression-free survival but not overall survival in this placebo-controlled trial.
Medicaid, the ACA, and Breast Cancer Survival
Survival improved for patients with metastatic breast cancer in states that expanded Medicaid coverage, and the disparity between white and other racial/ethnic groups decreased.
Excess Risk for Venous Thromboembolism Persists for Months After COVID-19
But risks are less elevated for those who do not require hospitalization.
Ipilimumab/Nivolumab Not Superior to Chemotherapy in Gastric Cancer
Outcomes were not better with ipilimumab plus nivolumab in patients with CPS >5% and in all randomized patients.
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